Mercapto and seleno derivatives as inhibitors of nitric oxide synthase
US5985917A · kind A · utility
6Cited by
1References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 29, 1999 |
| Grant date | Nov 16, 1999 |
| Priority date | — |
| Expiry date | Mar 29, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention is directed to a pharmacologically acceptable composition for inhibiting nitric oxide synthase in a mammal, which includes a mercapto or seleno derivative and a pharmaceutically acceptable carrier. The invention also concerns a method of inhibiting nitric oxide synthase, selectively inhibiting the inducible isoform of nitric oxide synthase, and treating various conditions where there is an advantage in inhibiting nitric oxide biosynthesis. The method includes the step of administering to a mammal a mercapto or seleno derivative in pure form or in a pharmaceutically acceptable carrier.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.