Synthesis of cyclic peptides
US5990273A · kind A · utility
50Cited by
19References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 10, 1997 |
| Grant date | Nov 23, 1999 |
| Priority date | — |
| Expiry date | Nov 10, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A process for preparing and purifying cyclic peptides having disulfide moieties in a two step processing operation including reverse phase chromatography which simplifies synthesis and reduces production costs, yet produces high, quality yield. The improved process is particularly useful for the preparation of vasopressin and oxytocin and their respective derivatives and analogs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.