Cytotoxic T lymphocyte-inducing lipopeptides and methods of use

US5993823A · kind A · utility

Assignee

• INSTITUT PASTEUR DE LILLE · FR

Inventors

• Christophe Boutillon · Lille, FR
• Frederic Martinon · Montrouge, FR
• Christian Sergheraert · Hazebrouck, FR
• Remy Magne · Marly-le-Roi, FR
• Helene Gras-Masse · Mérignies, FR
• Elisabeth Gomard · Paris, FR
• Andre Tartar · Pacé, FR
• Jean-Paul Levy · Paris, FR

Key dates

• Filing date: Jun 7, 1995
• Grant date: Nov 30, 1999
• Expiry date: Jun 7, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2740/16322
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Cytotoxic lymphocyte-inducing lipopeptides comprising a peptide fragment having approximately between 10 and 40 amino acids and comprising at least one antigenic determinant and also comprising one or more chains derived from fatty acids and one or more modified steroid groups useful for immunizing a human or animal body against pathogenic agents such as viruses or parasites which fragment is preferably a fragment of the protein encoded by the ENV gene, by the NEF gene or by the GAG gene of HIV viruses.