Patent · US Expired

Delayed drug-releasing microspheres

US5993855A · kind A · utility

147Cited by
0References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 18, 1996
Grant dateNov 30, 1999
Priority date
Expiry dateSep 18, 2016

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P9/08
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Microspheres prepared by emulsifying an aqueous phase containing a drug and an oil phase containing a biodegradable polymer to form a W/O emulsion, and then mixing and agitating this emulsion with another aqueous phase constituting a continuous phase to form a W/O/W emulsion. These microspheres can release a major portion of the drug after a predetermined period of time has elapsed after their administration to the patient, and are especially suitable for intracerebral implantation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.