NSADI delivery employing a powdered hydrocolloid gum obtainable from higher plants
US5993860A · kind A · utility
1Cited by
33References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 13, 1997 |
| Grant date | Nov 30, 1999 |
| Priority date | — |
| Expiry date | Nov 13, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/192
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An oral-delivery pharmaceutical composition for reducing the gastric irritation effect of an NSAID in the upper GI tract of a mammal. The composition includes (a) a mucosal protective amount of a pharmaceutically-acceptable hydrocolloid gum obtainable from higher plants, (b) a dispersion-enhancing amount of another excipient and (c) a therapeutically-effective amount of an NSAID. Also disclosed is a process for preparing the composition and a method for reducing the gastric irritation effect of the NSAID by administering the composition. Also, disclosed is a composition particularly useful for preparing an aqueous suspension.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.