Patent · US Expired

Methods for preparing solid supports for hybridization and reducing non-specific background

US5994065A · kind A · utility

7Cited by
0References
33Claims
0Family size

Assignee

Inventor

Key dates

Filing dateOct 17, 1996
Grant dateNov 30, 1999
Priority date—
Expiry dateOct 17, 2016

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Q1/6834
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Methods related to solid supports for binding reactions are disclosed. The present invention provides procedures for prepaing solid supports, and their use in binding assays, such that non-specific background on the solid supports is reduced. The reduction of non-specific background permits the detection of low levels of specific binding which normally would be masked by the non-specific binding. The methods are applicable to a variety of target ligands and probes, including nucleic acids such as oligonucleotides.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.