Cell growth substrate polymer

US5994133A · kind A · utility

Assignees

• Novartis AG · CH
• COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION · AU

Inventors

• Gordon Francis Meijs · Melbourne, AU
• Bronwyn Glenice Laycock · Melbourne, AU
• Madeleine Clare Griffiths · Hornsby, AU
• Edith Cheong · Merang, MY
• John Gerard Steele · Parramatta, AU
• Graham Johnson · Parramatta, AU

Key dates

• Filing date: Jan 6, 1998
• Grant date: Nov 30, 1999
• Expiry date: Jan 6, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2533/30
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Cell growth substrate polymers are described which comprise a macromonomer of the formula (I): Q-(PFPE-L).sub.n-1 -PFPE-Q, wherein n is at least 1.0; each PFPE may be the same or different and is a perfluorinated polyether of the formula (II): --OCH.sub.2 CF.sub.2 O (CF.sub.2 CF.sub.2 O).sub.x (CF.sub.2 O).sub.y CF.sub.2 CH.sub.2 O--, wherein the CF.sub.2 CF.sub.2 O and CF.sub.2 O units may be randomly distributed or distributed as blocks throughout the chain and wherein x and y may be the same or different such that the molecular weight of the perfluoropolyether is in the range of from 242 to 4000, L is a difunctional linking group; and Q at each end of the macromonomer is the same or different and is a polymerizable group. The cell growth substrate polymers may be used in the production of comeal implants.