Patent · US Expired

Reagents, methods and kits for detecting trichloroethylene and perchloroethylene

US5994145A · kind A · utility

8Cited by
2References
4Claims
0Family size

Assignees

Inventors

Key dates

Filing dateMay 31, 1996
Grant dateNov 30, 1999
Priority date
Expiry dateMay 31, 2016

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10T436/23
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Reagents, immunoassay methods, and kits for detecting the presence or amount of trichloroethylene or perchloroethylene in a sample. Reagents include antibodies, immunogens for preparing antibodies, and assay conjugates. The immunogens elicit high affinity antibodies to trichloroethylene. The antibodies have minimal crossreactivity to other halogenated and aromatic hydrocarbons. The assay conjugates provide for sufficient binding of the antibody to the conjugate with maximum inhibition of that binding by free trichloroethylene and perchloroethylene in the sample. The reagents are useful in immunoassays to detect trichloroethylene and perchloroethylene, especially in environmental samples. Kits contain antibodies specific for trichloroethylene and perchloroethylene and assay conjugates.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.