Patent · US Expired

Arylsulfonamides as phospholipase A.sub.2 inhibitors

US5994398A · kind A · utility

11Cited by
15References
40Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 11, 1996
Grant dateNov 30, 1999
Priority date
Expiry dateDec 11, 2016

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D333/28
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Arylsulfonamides which have the general structure: with the symbols R.sup.1, R.sup.2, R.sup.3, R.sup.4, A and n representing the groups and integers provided in the detailed description are provided herein. These compounds have activity as inhibitors of phospholipase A2, inhibitors of cytokine release and as inhibitors of neurodegeneration.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.