Patent · US Expired

Methods for treatment of neuro--and nephro--disorders and therapeutic toxicities using aminothiol compounds

US5994409A · kind A · utility

17Cited by
8References
40Claims
0Family size

Assignees

Inventors

Key dates

Filing dateDec 9, 1997
Grant dateNov 30, 1999
Priority date
Expiry dateDec 9, 2017

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to new uses of S-2-(3-aminopropylamino)ethyl dihydrogen phosphorothioate, (amifostine) and other aminothiol compounds to treat and reverse toxicities caused by therapeutic agents, radiation treatment or diabetes. In particular, the invention provides a method for treating neurotoxicity and nephrotoxicity associated with the administration of chemotherapeutic agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.