Bis-aryl ethers, compositions containing such compounds and methods of treatment
US5994412A · kind A · utility
5Cited by
0References
6Claims
0Family size
Assignee
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Key dates
| Filing date | Jul 2, 1998 |
| Grant date | Nov 30, 1999 |
| Priority date | — |
| Expiry date | Jul 2, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/645
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A compound represented by the formula I is disclosed: ##STR1## or a pharmaceutically acceptable salt or hydrate thereof. The compound has inhibitory activity against the oncoprotein Raf. Also included are pharmaceutical compositions, methods of treating cancer, cultures of the producing fungal microorganism and methods of fermentative production of the compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.