Oncoprotein protein kinase
US5994513A · kind A · utility
7Cited by
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3Claims
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Key dates
| Filing date | Sep 8, 1998 |
| Grant date | Nov 30, 1999 |
| Priority date | — |
| Expiry date | Sep 8, 2018 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
An isolated polypeptide (JNK) characterized by having a molecular weight of 46 kD or 55 kD as determined by reducing SDS-PAGE, having serine and theonine kinase activity, phosphorylating the c-Jun N-terminal activation domain and polynucleotide sequences and method of detection of JNK are provided herein. JNK phosphorylates c-Jun N-terminal activation domain which affects gene expression from AP-1 sites.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.