Patent · US Expired

Intradermal drug delivery device

US5997501A · kind A · utility

769Cited by
25References
41Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 19, 1996
Grant dateDec 7, 1999
Priority date
Expiry dateAug 19, 2016

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61M2005/14268
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

An intradermal drug delivery device comprises a housing (301a, 301b) having a drug reservoir (312) therewithin and a gas generation chamber (313) separated from the reservoir (312) by a displaceable membrane (311). A microprocessor-controlled electrolytic cell (316a, 316b, 319) provides gas to expand the gas generation chamber (313) and thereby contract the reservoir (312). A hollow needle (310), communicating at an inner end thereof with the reservoir (312), extends from a lower surface (308) of the housing (301) such that contraction of the reservoir (312) forces drug to escape therefrom via the needle (310). The device permits delivery of drugs of relatively large molecular weights at slow controllable rates. A displaceable protective cover (303) is mounted in means (307) allowing movement of the cover (303) between extended and retracted positions (305, 306). The cover (303) has an adhesive lower surface (309) for attachment to the skin of a subject. In use, a release liner is removed, the device is pressed against the skin and the cover (303) snaps back to the retracted position (306), the needle (310) thereby piercing the skin. After use the housing (301) is pulled away and t…

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.