Methods of diagnosis by detecting polymorphisms in the TGF-.beta.1 promoter
US5998137A · kind A · utility
7Cited by
2References
19Claims
0Family size
Inventors
Key dates
| Filing date | Jan 17, 1997 |
| Grant date | Dec 7, 1999 |
| Priority date | — |
| Expiry date | Jan 17, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/81
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of diagnosis comprises determining genotype of a TGF-.beta.1 promoter-specific polmorphisms that have been identified are at positions -800bp and -509bp. The genotype determined is then used to assess predisposition or susceptibility to a number of diseases: osteoporosis, atherosclerosis, cancer and immune disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.