Delivery of nucleic acids
US5998192A · kind A · utility
4Cited by
0References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 19, 1997 |
| Grant date | Dec 7, 1999 |
| Priority date | — |
| Expiry date | Aug 19, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2810/851
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a recombinant viral particle capable of delivering a nucleic acid to mammalian cells, the particle including a member of a first specific binding pair capable of binding to a first receptor expressed on the surface of a cell so as to cause infection thereof, and a surface-exposed member of a second specific binding pair capable of binding to a second receptor generally not expressed on the surface of the cell, such that binding of the viral particle to the second receptor via the member of the second specific binding pair inhibits infection of the cell by the viral particle.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.