Patent · US Expired

9,10 disubstituted camptothecin derivatives with antitumor activity

US5998426A · kind A · utility

3Cited by
1References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 29, 1997
Grant dateDec 7, 1999
Priority date
Expiry dateSep 29, 2017

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P35/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to 9-amino-10-(1-naphthylsulfonyloxy)-20(S)-camptothecin, 9-amino-10-phenylsulfonyloxy-20(S)-camptothecin, 7-ethyl-9-amino-10-(p-toluensulfonyloxy)-20(S)-camptothecin, their pharmaceutically acceptable salts, a process for their preparation, pharmaceutically compositions comprising them and their use as antitumor agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.