Patent · US Expired

Piperidinyl compounds as NK1 or NK2 antagonists

US5998444A · kind A · utility

22Cited by
23References
12Claims
0Family size

Assignee

Inventor

Key dates

Filing dateNov 26, 1997
Grant dateDec 7, 1999
Priority date
Expiry dateNov 26, 2017

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D495/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of formula I ##STR1## wherein Q.sup.1, Q.sup.2, Q.sup.3, Q.sup.4, and Q.sup.5 have any of the meanings given in the specification, their N-oxides, and their pharmaceutically acceptable salts are nonpeptide antagonists of SP and NKA are useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for preparing the compounds of formula I and intermediates.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.