Patent · US Expired

Fluorescent enzyme substrates

US5998593A · kind A · utility

30Cited by
6References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 10, 1998
Grant dateDec 7, 1999
Priority date
Expiry dateMar 10, 2018

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2333/924
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Fluorescent enzyme substrates are provided. The substrates are derivatives of coumarin having an enzyme cleavable group at position 7 and a hydrophilic amide group at position 4. The compounds are highly water soluble, stable at ambient and reduced temperatures and fluoresce upon cleavage by an enzyme.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.