Anticancer (IV) complexes for oral administration and a method of making the same
US5998648A · kind A · utility
8Cited by
5References
6Claims
0Family size
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Key dates
| Filing date | Aug 14, 1998 |
| Grant date | Dec 7, 1999 |
| Priority date | — |
| Expiry date | Aug 14, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F15/0093
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Platinum (IV) complexes for oral administration represented by the structural formula ##STR1## where A--A is a symmetrical diamine that can chelate to platinum and is selected from the group consisting of ethylene diamine, t(.+-.)-1,2-diaminocyclohexane, 2,2-dimethyl-1,3-propanediamine, cyclohexane-1,1-dimethaneamine and tetrahydro-4H-pyran-4,4-dimethaneamine; and R is propionyl, butyryl or valeryl. These complexes are useful in the treatment of cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.