Transgenic fish and vectors therefor
US5998697A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Oct 20, 1994 |
| Grant date | Dec 7, 1999 |
| Priority date | — |
| Expiry date | Oct 20, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2267/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Sockeye salmon growth hormone genes Types 1 and 2, and sockeye histone and metallothionein gene promoters have been isolated and sequenced. Terminator sequences for the growth hormone gene have been found. Vectors containing these promoter and terminator sequences (and intermediate sequences) have been prepared and used to transform fish egg cells. Transformed fish egg cells have been grown into transgenic fish. In the case of inserted full-length growth hormone gene, both accelerated growth and early smoltification were observed. An aspect found beneficial is to combine homologous fish metallothionein or histone gene promoter with fish gene, preferably growth hormone gene, terminator in the same vector, for preparing transgenic fish.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.