Method and apparatus for imaging and sampling diseased tissue using autofluorescence
US5999844A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 23, 1997 |
| Grant date | Dec 7, 1999 |
| Priority date | — |
| Expiry date | Apr 23, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B5/0086
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method and apparatus for imaging body tissue utilizing autofluorescence. The apparatus includes an endoscope having a distal end, proximal end and a light processing unit located at the proximal end of the endoscope. The light processing unit accepts light in a spectral region from a light source and directs the light through the endoscope to the tissue located at the distal end of the endoscope. The light excites autofluorescence in the tissue. Optics located in the distal end of the endoscope collect the excited autofluorescence in a spatially resolved manner and routes it to the light processing unit which separates the emitted light from any reflected excitation light. A plurality of imaging detectors receive the emitted light. Each imaging detector is responsive to light in a different spectral band such that an image is generated and interpreted according to a plurality of independent measurements. An apparatus for sampling tissue includes an endoscopic device having a sampling device. The sampling device is capable of taking a plurality of tissue samples. Captive units are in communication with the sampling device such that each tissue sample is deposited in a separate cap…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.