Genetic modification of endothelial cells
US6001350A · kind A · utility
9Cited by
2References
6Claims
0Family size
Inventors
Key dates
| Filing date | Jun 7, 1995 |
| Grant date | Dec 14, 1999 |
| Priority date | — |
| Expiry date | Jun 7, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/13043
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Endothelial cells transduced with genetic material encoding a polypeptide or protein of interest and, optionally, a selectable marker, as well as methods for making and using the transduced endothelial cells are disclosed. Such endothelial cells are useful in improving the performance of vascular grafts and in delivering the encoded polypeptide or protein, such as an enzyme, a hormone, a receptor or a drug, to an individual.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.