Polymeric lamellar substrate particles for drug delivery
US6001395A · kind A · utility
32Cited by
3References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 30, 1998 |
| Grant date | Dec 14, 1999 |
| Priority date | — |
| Expiry date | Mar 30, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/917
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a composition for delivery of an active agent comprising a plurality of lamellar particles of a biodegradable polymer which is at least in part crystalline, and an active agent adsorbed to at least most of the particles. Preferably the biodegradablepolymer is at least 5% by weight crystalline. Preferred biodegradable polymers are poly(L-lactide) (L.PLA) or copolymers or blends of L.PLA. The particles are especially useful for the immobilization of antigens or allergens for vaccines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.