Chemokine NC28 (monocyte chemotactic protein-3, MCP-3) polypeptides and their recombinant production
US6001649A · kind A · utility
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Key dates
| Filing date | Sep 29, 1992 |
| Grant date | Dec 14, 1999 |
| Priority date | — |
| Expiry date | Sep 29, 2012 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A new chemotactic cytokine, NC28 or Monocyte Chemotactic Protein-3 (MCP-3), is provided. Fragments of the cytokine comprising its 13 C-terminal amino acids also exhibit chemotactic activity. The polypeptides may be used as anticancer agents or immunomodulators. DNA encoding the NC28/MCP-3 polypeptides, as well as corresponding vectors and recombinant expression systems, are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.