Patent · US Expired

Dihydropyridine NPY antagonists: cyanoguanidine derivatives

US6001836A · kind A · utility

22Cited by
4References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 26, 1998
Grant dateDec 14, 1999
Priority date
Expiry dateMay 26, 2018

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D401/14
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A series of non-peptidergic antagonists of NPY have been synthesized and are comprised of cyanoguanidine derivatives of 4-phenyl-1,4-dihydropyridines of Formula (I). ##STR1## As antagonists of NPY-induced feeding behavior, these compounds are expected to act as effective anorexiant agents in promoting weight loss and treating eating disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.