N-aryl and N-heteroarylurea derivatives as inhibitors of acyl coenzyme A: Cholesterol acyl transferase (ACAT)
US6001860A · kind A · utility
52Cited by
5References
5Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jan 17, 1995 |
| Grant date | Dec 14, 1999 |
| Priority date | — |
| Expiry date | Jan 17, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound of the formula ##STR1## and the pharmaceutically acceptable salts thereof, wherein R.sup.17, R.sup.18 and R.sup.1 are as defined below. The compounds of formula I are inhibitors of acyl coenzyme A: cholesterol acyltransferase (ACAT) and are useful as hypolipidemic and antiatherosclerosis agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.