Racemisation of amines
US6002045A · kind A · utility
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9Claims
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Key dates
| Filing date | Jun 12, 1998 |
| Grant date | Dec 14, 1999 |
| Priority date | — |
| Expiry date | Jun 12, 2018 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/582
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for racemising an optically-enriched chiral amine of the formula: R.sup.1 --CH(NR.sup.3 R.sup.4)--R.sup.2, wherein R.sup.1 is aromatic or unsaturated alkyl; R.sup.2 is aromatic or alkyl; and R.sup.3 and R.sup.4 are independently selected from hydrogen, alkyl and aryl; and wherein any combination(s) of two of the R groups may form a ring; comprises treatment of the optically-enriched amine with a metal hydroxide in an aprotic polar solvent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.