Quantitative microarray hybridizaton assays
US6004755A · kind A · utility
187Cited by
2References
17Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Apr 7, 1998 |
| Grant date | Dec 21, 1999 |
| Priority date | — |
| Expiry date | Apr 7, 2018 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6837
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods are provided for quantitative gene expression analysis. In the subject methods, end-labeled target nucleic acid is contacted with an array of probe molecules stably associated with the surface of a solid support under hybridization conditions sufficient to produce a hybridization pattern. The resultant hybridization pattern can be used to obtain a quantitative information about the genetic profile of the end-labeled target nucleic acid sample, as well as the physiological source from which it is derived. As such, the subject methods find use in a variety of applications.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.