Apolipoprotein A-I agonists and their use to treat dyslipidemic disorders

US6004925A · kind A · utility

Assignees

• J. L. Dasseux · FR
• R. Sekul · DE
• K. Buttner · DE
• I. Cornut · FR
• G. Metz · DE
• J. DuFourcq · FR

Inventors

• Jean-Louis Dasseux · Mannheim, DE
• Renate Sekul · Ladenburg, DE
• Klaus Büttner · Epfenbach, DE
• Isabelle Cornut · Edingen-Neckarhausen, DE
• Günther Metz · Edingen-Neckarhausen, DE
• Jean Dufourcq · Pessac, FR

Key dates

• Filing date: Sep 29, 1997
• Grant date: Dec 21, 1999
• Expiry date: Sep 29, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K7/08
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides peptides and peptide analogues that mimic the structural and pharmacological properties of human ApoA-I. The peptides and peptide analogues are useful to treat a variety of disorders associated with dyslipidemia.