Patent · US Expired

Use of von willebrand factor and pharmaceutical formulation

US6005077A · kind A · utility

19Cited by
4References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 6, 1996
Grant dateDec 21, 1999
Priority date
Expiry dateNov 6, 2016

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2333/755
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention relates to the use of von Willebrand Factor (vWF) with a prolonged biological half-life for the production of a preparation for stabilization of blood coagulation Factor VIII (FVIII:C) in a mammal. Additionally, a pharmaceutical preparation is provided comprising a biologically active FVIII:C/vWF complex with improved pharmokinetic properties, said complex containing a vWF with a prolonged biological half-life.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.