Imino compounds, process for their preparation and their use as victronectin antagonists

US6005117A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Volkmar Wehner · Bischofsheim a.d.Rhön, DE
• Jochen Knolle · Kriftel, DE
• Hans Ulrich Stilz · Frankfurt am Main, DE
• Jean-Francois Gourvest · Claye-Souilly, FR
• Denis Carniato · Marcoussis, FR
• Thomas Gadek · Oakland, US
• Robert McDowell · San Francisco, US
• Robert Pitti · Corona, US
• Sarah C. Bodary · San Francisco, US

Key dates

• Filing date: Jul 24, 1997
• Grant date: Dec 21, 1999
• Expiry date: Jul 24, 2017

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

There are described imino derivatives of formula (I) EQU R.sup.1 --Y--A--B--D--E--F--G (I) their preparation and their use as medicaments. The compounds according to the invention may be used as vitronectin receptor antagonists and as inhibitors of bone resorption.