Enantioselective oxazaborolidine catalysts
US6005133A · kind A · utility
2Cited by
4References
4Claims
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Inventor
Key dates
| Filing date | Oct 10, 1995 |
| Grant date | Dec 21, 1999 |
| Priority date | — |
| Expiry date | Oct 10, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2602/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The enantioselective borane reduction of prochiral ketones to optically pure alcohols is effectively achieved by performing the reduction in the presence of catalytic amounts of the new and valuable oxazaborolidine compounds of formulae (I) and (II). The compounds of formulae (I) and (II) may be isolated and purified prior to use in the reduction reactions or the compounds of formulae (I) and (II) may be generated in situ.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.