Hydrophilic binary systems for the administration of lipophilic compounds

US6008192A · kind A · utility

Assignee

• Abbott Laboratories · US

Inventors

• Laman A. Al-Razzak · Libertyville, US
• Panayiotis P. Constantinides · Gurnee, US
• Dilip Kaul · Gurnee, US
• John M. Lipari · Racine, US
• Lisa McChesney-Harris · Cicero, US
• Bashar Abdullah · Carp, CA

Key dates

• Filing date: Mar 12, 1998
• Grant date: Dec 28, 1999
• Expiry date: Mar 12, 2018

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Binary pharmaceutical compositions comprising (i) a cyclosporine compound, (ii) a hydrophilic phase and (iii) a surfactant provide bioavailability of the active ingredient which is equivalent to that provided by ternary compositions, but without the need for a lipophilic phase.