S. aureus fibrinogen binding protein gene

US6008341A · kind A · utility

Assignee

• THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN · IE

Inventors

• Timothy J. Foster · Dublin, IE
• Damien McDevitt · Berwyn, US

Key dates

• Filing date: Aug 22, 1994
• Grant date: Dec 28, 1999
• Expiry date: Aug 22, 2014

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P31/04
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The isolation of the S. aureus fibrinogen binding protein gene is described and a minimal fibrinogen binding protein is identified. The protein finds use as a vaccine or a pharmaceutical composition for application to prevent infection, promotion of wound healing, blocking adherence to indwelling medical devices, or diagnosis of infection.