Assay for collagen degradation
US6010863A · kind A · utility
5Cited by
1References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 16, 1997 |
| Grant date | Jan 4, 2000 |
| Priority date | — |
| Expiry date | Sep 16, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/975
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The patent application describes a sandwich-type immunoassay for the detection and/or quantitation of collagen degradation products in biological samples such as blood, serum, plasma, sputum and cell cultures. The immunoassay uses a first antibody directed at an epitope present on a collagen molecule at a distance of up to 165 amino acids from a collagen telopeptide crosslink site, and a second antibody directed at another epitope of the crosslinked collagen molecule.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.