Peptide T and related peptides in the treatment of inflammation, including multiple sclerosis

US6011014A · kind A · utility

Assignee

• Advanced Immuni T, Inc. · US

Inventors

• Anders Jorgen Andersen · Kokkedal, DK
• Roger Aston · Gloucester, GB
• Peter Louis Carlen · Schreiber, CA
• Penelope Reed Doob · Schreiber, CA
• Douglas Kevin MacFadden · Schreiber, CA
• David James Phipps · Toronto, CA
• Deborah Rathjen · Forbes, AU
• Fred Widmer · Forbes, AU

Key dates

• Filing date: May 21, 1998
• Grant date: Jan 4, 2000
• Expiry date: May 21, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N2740/16122
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method of treating or preventing multiple sclerosis in a patients in need of such treatment by administering an effect amount of the peptide: I-A-B-C-D-E-F-G-H-II (General Formula) wherein A is Ala, Gly, Val, Ser, Thr or absent, B is Ala, Gly, Val, Ser, Thr or absent, C is Ser, Thr or absent, D is Ser, Thr, Asn, Glu, Arg, IIe, Leu or absent, E is Ser, Thr, Asp or absent, F is Thr, Ser, Asn, Glu, Lys, Trp or absent, G is tyr or absent; H is Thr, Arg, Gly, Met, Met(O), Gys, Thr, Gly or absent, I is Cys or absent, II is Cys, an amide group, substituted amide group, an ester group or absent.