Chiral phenyldihydrofuranones as PDE-IV inhibitors

US6011060A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Henry Laurent
• Peter Esperling · Berlin, DE
• Kurt Hamp · Berlin, DE
• Herbert Schneider · Berlin, DE
• Helmut Wachtel · Berlin, DE

Key dates

• Filing date: Dec 11, 1998
• Grant date: Jan 4, 2000
• Expiry date: Dec 11, 2018

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C45/71
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Described are racemic and enantiomerically pure chiral phenyldihydrofuranones, their preparation and their use in drugs (selective inhibition of the cAMP-specific phosphodiesterase IV).