Hybridomas and monoclonal antibodies that specifically bind to glutamic acid decarboxylase peptides

US6011139A · kind A · utility

Assignee

• The Regents of the University of California · US

Inventors

• Allan J. Tobin · Los Angeles, US
• Mark G. Erlander · Encinitas, US
• Daniel L. Kaufman · Santa Monica, US

Key dates

• Filing date: Jun 7, 1995
• Grant date: Jan 4, 2000
• Expiry date: Jun 7, 2015

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S435/975
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Isolated polypeptides useful in ameliorating GAD-associated autoimmune disease as well as diagnostic and therapeutic methods of using the peptides are disclosed. Monoclonal antibodies specific for GAD peptides and hybridoma cells producing such are also disclosed.