Production of .sup.64 Cu and other radionuclides using a charged-particle accelerator
US6011825A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 9, 1996 |
| Grant date | Jan 4, 2000 |
| Priority date | — |
| Expiry date | Aug 9, 2016 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG21G2001/0094
- WIPO fieldEngines, pumps, turbines
- WIPO sectorMechanical engineering
Abstract
Radionuclides are produced according to the present invention at commercially significant yields and at specific activities which are suitable for use in radiodiagnostic agents such as PET imaging agents and radiotherapeutic agents and/or compositions. In the method and system of the present invention, a solid target having an isotopically enriched target layer electroplated on an inert substrate is positioned in a specially designed target holder and irradiated with a charged-particle beam. The beam is preferably generated using an accelerator such as a biomedical cyclotron at energies ranging from about 5 MeV to about 25 MeV. The target is preferably directly irradiated, without an intervening attenuating foil, and with the charged particle beam impinging an area which substantially matches the target area. The irradiated target is remotely and automatically transferred from the target holder, preferably without transferring any target holder subassemblies, to a conveyance system which is preferably a pneumatic or hydraulic conveyance system, and then further transferred to an automated separation system. The system is effective for processing a single target or a plurality of ta…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.