Patent · US Expired

Pancreas-derived serpin

US6013448A · kind A · utility

37Cited by
1References
2Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 25, 1997
Grant dateJan 11, 2000
Priority date
Expiry dateNov 25, 2017

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention provides nucleotide and amino acid sequences that identify and encode a novel pancreas-derived serpin (PDS) expressed in human pancreas. The present invention also provides for antisense molecules to the nucleotide sequences which encode PDS, expression vectors for the production of purified PDS, antibodies capable of binding specifically to PDS, hybridization probes or oligonucleotides for the detection of PDS-encoding nucleotide sequences, genetically engineered host cells for the expression of PDS, diagnostic tests based on PDS-encoding nucleic acid molecules and a pharmaceutical composition containing PDS capable of binding specifically to a serine protease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.