Thiol sulfone metalloprotease inhibitors
US6013649A · kind A · utility
17Cited by
5References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 22, 1997 |
| Grant date | Jan 11, 2000 |
| Priority date | — |
| Expiry date | Jul 22, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention is directed to proteinase (protease) inhibitors, and more particularly to thiol sulfone inhibitors for matrix metalloproteinase 13(MMP-13), compositions of proteinase inhibitors, intermediates for the syntheses of proteinase inhibitors, processes for the preparation of proteinase inhibitors and processes for treating pathological conditions associated with pathological matrix metalloproteinase activity related to MMP-13.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.