Process for preparation of glycosides of tumor-associated carbohydrate antigens
US6013779A · kind A · utility
19Cited by
17References
23Claims
0Family size
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Key dates
| Filing date | Mar 18, 1997 |
| Grant date | Jan 11, 2000 |
| Priority date | — |
| Expiry date | Mar 18, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H15/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Glycoconjugate antigens are prepared by preparing a hapten glycoside, especially an alpha glycoside prepared by the Fischer method, with an olefinic aglycon moiety, especially one having a non-terminal double bond, ozonolyzing the hapten glycoside with an olefinic aglycon moiety having a non-terminal double bond to form a hapten-glycoside derivative, preferably without producing Germaldehyde as a byproduct removing by-products of ozonolysis, and conjugating the hapten-glycoside derivative to a carrier.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.