Continuous release polymeric implant carrier
US6013853A · kind A · utility
236Cited by
53References
36Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 15, 1994 |
| Grant date | Jan 11, 2000 |
| Priority date | — |
| Expiry date | Feb 15, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2250/003
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Biodegradable, porous, polymeric implant material provides substantially continuous release of bioactive agent during in vivo use. Bioactive agent is initially released in amounts that are less than degradation rate of polymer, thereby promoting migration of cells into material. Later larger amounts of bioactive agent is released, thereby promoting differentiation of cells. Method of making material includes step of applying vacuum to form pores. Implant material may be adapted for one phase implant (e.g., for bone or cartilage) or for two phase layered implant (e.g., for cartilage layer on top of bone layer).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.