Preparation of further diagnostic agents
US6015546A · kind A · utility
63Cited by
44References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 5, 1995 |
| Grant date | Jan 18, 2000 |
| Priority date | — |
| Expiry date | Jun 5, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K49/223
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Microcapsules are prepared by a process comprising the steps of (i) spray-drying a solution or dispersion of a wall-forming material in order to obtain intermediate microcapsules and (ii) reducing the water-solubility of at least the outside of the intermediate microcaspsules. Suitable wall-forming materials include proteins such as albumin and gelatin. The microcapsules have walls of 40-500 nm thick and are useful in ultrasonic imaging. The control of median size, size distribution and degree of insolubilization and cross-linking of the wall-forming material allows novel microsphere preparations to be produced.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.