CDC37 cell-cycle regulatory protein and uses related thereto
US6015692A · kind A · utility
14Cited by
1References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 9, 1997 |
| Grant date | Jan 18, 2000 |
| Priority date | — |
| Expiry date | May 9, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the discovery in mammalian cells, particularly human cells, of a novel CDK-binding protein, referred to herein as "cdc37". As described herein, this protein functions to facilitate activation and accordingly finctions in the modulation of cell-cycle progression, and therefore ultimately of cell growth and differentiation. Moreover, binding data indicated that cdc37 may function coordinately with other cell-cycle regulatory proteins, such as of cyclin-dependent kinases (CDKs), src, p53 and erk kinases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.