Dihalogenated ferrocenes and processes for the preparation thereof

US6015919A · kind A · utility

Assignee

• Novartis AG · CH

Inventor

• Benoit Pugin · Münchenstein, CH

Key dates

• Filing date: Feb 8, 1999
• Grant date: Jan 18, 2000
• Expiry date: Feb 8, 2019

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02P20/50
• WIPO field: Chemical engineering
• WIPO sector: Chemistry

Abstract

The invention relates to a compound of formula I ##STR1## R.sub.1 is C.sub.1 -C.sub.8 alkyl, phenyl or phenyl substituted by from 1 to 3 C.sub.1 -C.sub.4 alkyl or C.sub.1 -C.sub.4 alkoxy substituents; PA1 R.sub.2 and R.sub.3 are each independently of the other hydrogen or C.sub.1 -C.sub.12 alkyl; and PA1 Hal is F, Cl, Br or I. Compounds of formula I are valuable intermediates for compounds of formula III which are also a subject of this invention: ##STR2## R.sub.1, R.sub.2, R.sub.3 and Hal are as defined above; R.sub.10 and R.sub.11 are identical or different and are C.sub.1 -C.sub.12 alkyl, C.sub.5 -C.sub.12 cycloalkyl, phenyl, C.sub.5 -C.sub.12 cycloalkyl substituted by C.sub.1 -C.sub.4 alkyl or by C.sub.1 -C.sub.4 alkoxy, or phenyl substituted by from one to three C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, --SiR.sub.4 R.sub.5 R.sub.6, halogen, --SO.sub.3 M, --CO.sub.2 M, --PO.sub.3 M, --NR.sub.7 R.sub.8, --[.sup.+ NR.sub.7 R.sub.8 R.sub.9 ]X.sup.- or C.sub.1 -C.sub.5 fluoroalkyl substituents; or PA1 the group --PR.sub.10 R.sub.11 is a radical of formula IV, IVa, IVb or IVc ##STR3## R.sub.4, R.sub.5 and R.sub.6 are each independently of the others C.sub.1 -C.sub.12 alkyl or…