Liposomogenic UV absorbers

US6017556A · kind A · utility

Assignee

• Ciba Specialty Chemicals Corporation · US

Inventors

• Helmut Luther · Weil am Rhein, DE
• Dietmar Huglin · Eimeldingen, DE
• Robert Hochberg · Glückstadt, DE

Key dates

• Filing date: Sep 16, 1997
• Grant date: Jan 25, 2000
• Expiry date: Sep 16, 2017

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2800/57
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The use of liposomogenic UV absorbers for protecting human hair from the damaging effect of UV radiation is described. The liposomogenic UV absorbers comprise a hydrophilic head group (=Z), a spacer (=W), a UV chromophore (Q) having an absorption in the range from 285 to 400 nm and at least one hydrophobic tail group (=A). They have the formula ##STR1## in which A.sub.1 and A.sub.2 independently of one another are a hydrophobic radical; PA1 Q is a UV chromophore; PA1 W is an organic radical; PA1 Z.sub.1 and Z.sub.2 independently of one another are a hydrophilic radical; n.sub.1 and n.sub.2 independently of one another are a number from 0 to 4, where n.sub.1 =n.sub.2 = is not included; PA1 p is 1 or 2; PA1 q is a number from 0 to 3; PA1 r.sub.1 is 1 or 2; PA1 r.sub.2 is 0 or 1; and PA1 s.sub.1 is a number from 1 to 3. The liposomogenic UV absorbers are capable of self-organization into bimolecular layers, and can as a result penetrate into the stratum corneum to a high degree and are extremely resistant to washing out there.