Patent · US Expired

2,1,3-benzothia(OXA)diazole derivatives having an endothelin receptor antagonistic effect

US6017939A · kind A · utility

1Cited by

0References

21Claims

0Family size

Assignee

Merck Patentgesellschaft · DE

Inventors

Dieter Dorsch · Ober-Ramstadt, DE
Mathias Osswald · Zwingenberg, DE
Werner Mederski · Zwingenberg, DE
Claudia Wilm · Darmstadt, DE
Claus J. Schmitges · Groß-Umstadt, DE
Maria Christadler · Darmstadt, DE
Soheila Anzali · Groß-Zimmern, DE

Key dates

Filing date	Nov 12, 1998
Grant date	Jan 25, 2000
Priority date	—
Expiry date	Nov 12, 2018

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D417/14
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The invention concerns compounds of formula (I), in which R is (i), (ii) or (iii); n is 0, 1 or 2; X means O or S; and R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have different meanings, or a cyclized tautomeric shape. The invention also concerns the (E) isomers and salts of these compounds which display endothelin receptor antagonistic properties. ##STR1##

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.