Patent · US Expired

Aryl furan derivatives as PDE IV inhibitors

US6020339A · kind A · utility

54Cited by
10References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 28, 1998
Grant dateFeb 1, 2000
Priority date
Expiry dateSep 28, 2018

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07F7/0814
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The invention encompasses the novel compound of Formula I useful in the treatment of diseases, including asthma, by raising the level of cyclic adenosine-3',5'-monophosphate (cAMP) through the inhibition of phosphodiesterase IV (PDE IV). ##STR1## The invention also encompasses certain pharmaceutical compositions and methods for treatment of diseases by inhibition of PDE IV, resulting in an elevation of cAMP, comprising the use of compounds of Formula I.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.