Therapeutic suppression of specific immune responses by administration of oligomeric forms of antigen of controlled chemistry
US6022544A · kind A · utility
17Cited by
10References
28Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 21, 1995 |
| Grant date | Feb 8, 2000 |
| Priority date | — |
| Expiry date | Feb 21, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2039/6093
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention features a method for reducing an undesired antibody response in a mammal by administering to the mammal a non-immunogenic construct which is free of high molecular weight immunostimulatory molecules. The construct which contains at least two copies of a B cell membrane immunoglobulin receptor epitope bound to a pharmaceutically acceptable non-immunogenic carrier directly binds to B cell membrane immunoglobulin receptors but fails to form an immunon.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.